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>   home   >   Products   >   Primary Antibodies   >   Anti-Pig CD46 Antibody, clone 6D8/8    

Anti-Pig CD46 Antibody, clone 6D8/8

Mouse Anti-Pig Monoclonal Antibody

  • FC - Anti-Pig CD46 Antibody, clone 6D8/8  ABD11756
    Staining of porcine peripheral blood lymphocytes with Mouse anti Porcine CD46: FITC
  • FC - Anti-Pig CD46 Antibody, clone 6D8/8  ABD11756
    Staining of porcine peripheral blood granulocytes with Mouse anti Porcine CD46
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O02839
Reactivity Pig
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 6D8/8
Calculated MW 39692 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Porcine peripheral blood mononuclear cells.
Shelf Life 18 months from date of despatch.
Gene ID 396922
Other Names Membrane cofactor protein, CD46, CD46, MCP
Target/Specificity Mouse anti-Pig CD46, clone 6D8/8 recognizes the porcine CD46 cell surface antigen, a ~50-60 kDa glycoprotein also known as membrane cofactor protein (MCP).Porcine CD46 is expressed on a wide range of cells including leucocytes, platelets and erythrocytes. CD46 serves as an inhibitor of complement activation on host cells.Clone 6D8/8 is reported to induce homotypic cell aggregation, (Bullidoet al.2000). .Mouse anti-pig CD46, clone 6D8/8 detects a series of closely apposed bands of approximately 50-60 kDa in pig erythrocyte lysates (Perez De La Lastra et al.1999).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Pig CD46 Antibody, clone 6D8/8 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Bullido, R. et al. (2000) Induction of aggregation in porcine lymphoid cells by antibodies to CD46.
Vet. Immunol. Immmunopathol. 73:73-81. 2. Perez de la Lastra, J.M. et al. (1999) Epitope mapping of 10 monoclonal antibodies against the pig analogue of human membrane cofactor protein (MCP).
Immunology 96: 663-670. 3. Dräger, C. et al. (2015) Porcine complement regulatory protein CD46 and heparan sulfates are the major factors for classical swine fever virus attachment in vitro.
Arch Virol. 160 (3): 739-46.1. Piriou-Guzylack, L. (2008) Membrane markers of the immune cells in swine: an update.
Vet Res. 39: 54.

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Cat# ABD11756
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