|Application ||WB, E|
|Other Accession||P02679, P02675|
|Calculated MW||94973 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Homogenised fibrin clot|
|Shelf Life||18 months from date of despatch.|
|Other Names||Fibrinogen alpha chain, Fibrinopeptide A, Fibrinogen alpha chain, FGA|
|Target/Specificity||Mouse anti-Human D-Dimer antibody, clone DD3 recognizes human D-dimer and high molecular weight fibrin degradation products, but does not cross-react with fibrinogen (D-monomer).D-dimers are the principle degradation products of cross-linked fibrin, released into the bloodstream following the digestion of fibrin clots (thrombus) by the enzyme plasmin, and thus measurement of the level of D-dimer in plasma, can be used as an indication of thrombotic disorders. Conditions in which levels of D-dimer are elevated include deep vein thrombosis (DVT), venous thromboembolism (VTE), cardiovascular disease and disseminated intravascular coagulation (DIC), a possible acute condition arising from surgical operations, septic shock and liver disease.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human D-Dimer Antibody, clone DD3 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Rowbotham, B.J. et al. (1987) Measurement of crosslinked fibrin derivatives--use in the diagnosis of venous thrombosis.Thromb. Haemost. 57: 59-61. 2. Kruskal, J.B. et al. (1992) Elevated fibrin-related and fibrinogen-related antigens in patients with liver disease. Hepatology. 16: 920-923.
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