|Application ||WB, E|
|Purification||Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||ABD11811 recognises both male and female ether extracted parasite antigen of canine heartworm.Canine heartworm infection, caused by the filarial nematode Dirofilaria immitis, is an insidious and potentially fatal condition transmitted by mosquitoes, which primarily affects the heart and lungs of dogs, but may also affect other species including cats, foxes, sea-lions, ferrets and humans.Canine heartworm disease, resulting ultimately in damage to the pulmonary vasculature system, is largely attributed to the immunological response of the host to the presence of the adult parasites, and in many cases their microscopic offspring (microfilaria) which circulate in the bloodstream, but growing evidence suggests the involvement of further factors/mediators.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Canine Heartworm Antibody, clone HW1-39 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Mupanomunda, M. et al. (1997) Dirofilaria immitis: heartworm infection alters pulmonary artery endothelial cell behaviour. J. Appl. Physiol. 82: 389-398.2. Uchide, T. and Saida, K. (2005) Elevated endothelial-1 expression in dogs with heartworm disease. J. Vet. Med. Sci. 67: 1155-1161.
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