|Application ||WB, E|
|Calculated MW||19909 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||E. coli-derived recombinant protein corresponding to full-length (aa1-173) human crystallin alpha A.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Alpha-crystallin A chain, Heat shock protein beta-4, HspB4, Alpha-crystallin A(1-172), Alpha-crystallin A(1-168), Alpha-crystallin A(1-162), CRYAA, CRYA1, HSPB4|
|Target/Specificity||ABD11868 recognises alpha A crystallin, a 20kDa water-soluble major structural protein and member of the heat shock protein family, designated HSPB4, which acts as a molecular chaperone and is believed to play a role in the maintenance of ocular lens transparency/refractive index. Besides the involvement of both alpha A and alpha B crystallin in the prevention of protein precipitation and cataract formation in the eye, alpha crystallins have also been demonstrated in other tissues including the heart, brain, kidney, spleen and thymus.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Human alpha A Crystallin Antibody, clone c9F2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Andley, U. P. et al. (1996) Cloning, expression, and chaperone-like activity of human alphaA-crystallin. J. Biol. Chem. 271: 31973-31980.
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