|Application ||IF, FC, E|
|Clone Names||BEL 0126|
|Purification||Purified IgG prepared by affinity chromatography on Protein A.|
|Immunogen||Purified cryptosporidium oocysts from bovine faeces.|
|Shelf Life||18 months from the date of despatch.|
|Target/Specificity||Mouse anti-Cryptosporidium antibody, clone BEL 0126 recognizes a membrane antigen expressed by the oocysts of Cryptosporidium sp., an obligate enteric coccidian parasite of the phylum Apicomplexa that infects the gastrointestinal tract. The parasite is one of the most important enteric pathogens in both humans and animals (Roseet al.2002). Since its first diagnosis in 1975 (Meiselet al.1976), Cryptosporidiosis, has become one of the most prominent public health concerns worldwide (Roseet al.2002).Cryptosporidium oocysts are resistant to chlorine and their small size makes removal by filtration difficult. Alternative methods have been developed such as UV and ozone treatment alongside monitoring using Immunofluorescence screening (Roseet al.2002).Cryptosporidiosis is a disease affecting the intestines of mammals which is spread through the fecal-oral route. The main symptom of is self-limiting diarrhea in people with intact immune systems. However, in immunocompromised individuals, such as AIDS patients, infection can cause permanent & life-threatening diarrhea (Maet al.1984).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Cryptosporidium Antibody, clone BEL 0126 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Mansfield, K.G. et al. (1997) Identification of an Enterocytozoon bieneusi-like microsporidian parasite insimian-immunodeficiency-virus-inoculated macaques with hepatobiliary disease.Am J Pathol. 150: 1395-405.1. Meisel, J.L. et al. (1976) Overwhelming watery diarrhea associated with a cryptosporidium in an immunosuppressed patient.Gastroenterology. 70: 1156-60.2. Rose, J.B. et al. (2002) Risk and control of waterborne cryptosporidiosis.FEMS Microbiol Rev. 26: 113-23.3. Ma, P. (1984) Cryptosporidium and the enteropathy of immune deficiency.J. Pediatr. Gastroenterol. Nutr. 3: 488-90.
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