|Application ||WB, E|
|Calculated MW||17490 Da|
|Purification||Antiserum to mouse IL-17 were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant mouse IL-17|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Interleukin-17A, IL-17, IL-17A, Cytotoxic T-lymphocyte-associated antigen 8, CTLA-8, Il17a, Ctla8, Il17|
|Target/Specificity||Rabbit anti-Mouse Interleukin-17 antibody recognizes mouse interleukin-17 (IL-17/IL-17A), a disulfide-linked homodimer and member of the IL-17 family, secreted primarily by activated CD4+ T cells, which signals through the IL-17 receptor (IL-17R).IL-17 induces a variety of target cells to secrete inflammatory cytokines, including IL-1beta, IL-6, TNFalpha, IFNgamma and granulocyte colony-stimulating factor, as well as synergizing with other inflammatory cytokines and agonists. Increased levels of IL-17 are detectable during transplant rejection, and also during rheumatoid arthritis, possibly contributing to bone destruction.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Mouse Interleukin-17 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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