|Application ||WB, IHC-F, IF, E, Func|
|Calculated MW||22854 Da|
|Purification||Antisera to rat CNTF were raised by repeated immunisations of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant rat CNTF|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Ciliary neurotrophic factor, CNTF, Cntf|
|Target/Specificity||Rabbit anti-Rat CNTF antibody recognizes rat ciliary neurotrophic factor (CNTF)...Rat CNTF is a 22.7kD neuroregulatory cytokine which is found primarily in peripheral nerve tissue. CNTF promotes the survival and differentiation of neurons and other neuronal cell types.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Rat CNTF Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Fischer, D. et al. (2008) Crystallins of the beta/gamma-superfamily mimic the effects of lens injury and promote axon regeneration. Mol Cell Neurosci. 37: 471-9. 2. Leibinger, M. et al. (2009) Neuroprotective and axon growth-promoting effects following inflammatory stimulation on mature retinal ganglion cells in mice depend on ciliary neurotrophic factor and leukemia inhibitory factor.J Neurosci. 29: 14334-41. 3. Sengottuvel, V. et al. (2011) Taxol facilitates axon regeneration in the mature CNS.J Neurosci. 31: 2688-99. 4. Müller, A. et al. (2007) Astrocyte-derived CNTF switches mature RGCs to a regenerative state following inflammatory stimulation.Brain. 130: 3308-20. 5. Hauk, T.G. et al. (2010) Stimulation of axon regeneration in the mature optic nerve by intravitreal application of the toll-like receptor 2 agonist Pam3Cys.Invest Ophthalmol Vis Sci. 51: 459-64.
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