|Application ||WB, E|
|Calculated MW||7697 Da|
|Purification||Antiserum to human defensin beta 3 was raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared by affinity chromatography.|
|Immunogen||Recombinant human defensinβ-3|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Beta-defensin 103, Beta-defensin 3, BD-3, DEFB-3, HBD3, hBD-3, Defensin, beta 103, Defensin-like protein, DEFB103A, BD3, DEFB103, DEFB3|
|Target/Specificity||Rabbit anti-human Defensinβ-3 polyclonal antibody specifically recognizes human defensin beta 3 (BD-3), a 45aa ~5kDa cationic non-haemolytic antimicrobial peptide expressed by epithelial cells and member of the beta-defensin family. Defensin beta 3 is highly expressed in the skin and tonsils and at lower levels in other tissues(Harderet al.2001).Defensin beta 3 plays an important role in the innate immune response to potentially pathogenic microbes, including multiresistantS. aureus and vancomycin-resistant E. faecium.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Defensin beta 3 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Boesch, A.W. et al. (2013) A Multiplexed Assay to Detect Antimicrobial Peptides in Biological Fluids and Cell Secretions.J Immunol Methods. pii: S0022-1759(13)00241-X.1. Harder, J. et al. (2001) Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.J Biol Chem. 276: 5707-13.
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