|Application ||WB, E|
|Calculated MW||16600 Da|
|Purification||Antiserum to human PSPN were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.|
|Immunogen||Recombinant human Persephin|
|Shelf Life||12 months from date of reconstitution.|
|Other Names||Persephin, PSP, PSPN|
|Target/Specificity||Rabbit anti-Human Persephin antibody specifically recognizes human Persephin (PSPN), a neurotrophic protein and member of the Glial cell line-derived neurotrophic factor (GDNF) family, which plays a key role in the development of the central nervous system (CNS).PSPN is synthesized throughout the nervous system, and promotes ventral midbrain dompaminergic neuron survival and ureteric bud branching, but unlike GDNF and Neurturin, does not support peripheral neuron survival. PSPN signals through a multicomponent complex consisting of the binding receptor GFRalpha4, co-expressed with the signalling Ret receptor tyrosine kinase.|
|Preservative & Stabilisers||Preservative Free|
|Storage||Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.|
|Precautions||Anti-Human Persephin Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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