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Anti-Human WNT-3a Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC - Anti-Human WNT-3a Antibody  ABD11966
    Formlin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Rabbit anti Human WNT-3a following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
  • IHC-P - Anti-Human WNT-3a Antibody  ABD11966
    Formlin fixed, paraffin embedded human breast invasive ductal carcinoma stained with Rabbit anti Human WNT-3a following heat mediated antigen retrieval using sodium citrate buffer (pH6.0)
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P56704
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 39365 Da
Additional Information
Purification Antiserum to human WNT-3a were raised by repeated immunisation of rabbits with highly purified antigen. Purified IgG was prepared from whole serum by affinity chromatography.
Immunogen Recombinant human WNT-3a
Shelf Life 12 months from date of reconstitution.
Gene ID 89780
Other Names Protein Wnt-3a, WNT3A
Target/Specificity Rabbit anti-Human WNT-3a antibody specifically recognizes human WNT-3a, a secreted protein and member of the Wnt family of signalling proteins, which acts as a ligand for members of the frizzled family of seven transmembrane receptors, and plays key roles in many developmental and cell fate decisions, including embryonic patterning, CNS development, and cytoskeletal formation. Wnt-3a acts as a promoter of the proliferation of ventral midbrain dopaminergic neuron precursor cells, and has been implicated in the progressive differentiation of anterior neural cells, as well as regulating the survival and expansion of neural progenitors derived from human embryonic stem cells. Wnt3a has been shown to act upstream of the Notch signalling pathway, in the regulation of somitogenesis, which is believed to be controlled by a segmentation clock, consisting of molecular oscillators in the Notch, Wnt3a and Fgf8 pathways.
Preservative & Stabilisers Preservative Free
Storage Prior to reconstitution store at +4℃. Following reconstitution store at -20℃.
PrecautionsAnti-Human WNT-3a Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Lai, Y.H. et al. (2011) SOX4 interacts with plakoglobin in a Wnt3a-dependent manner in prostate cancer cells.
BMC Cell Biol. 12: 50.2. Yan, L. et al. (2011) Activation of the canonical Wnt/ß-catenin pathway in ATF3-induced mammary tumors.
PLoS One. 6:e16515.

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Cat# ABD11966
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