|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Density gradient enriched PVG rat thoracic duct dendritic cells.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Rat OX-62 antibody, clone OX-62 recognizes the OX-62 antigen, shown to be rat alpha E2 integrin which is expressed by dendritic cells of dendritic epidermal T cells, intraepithelial lymphocytes in the small intestine and by cells of dendritic morphology in lymphoid organs, at sites where gamma delta T cells are present.|
|Preservative & Stabilisers||0.09% Sodium Azide; 1% Bovine Serum Albumin|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Rat OX-62 Antibody, clone OX-62 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Brenan, M. and Puklavec, M. (1992) The MRC OX-62 Antigen: A useful marker in the purification of rat veiled cells with the biochemical properties of an integrin.J. Exp. Med. 175: 1457-1465. 2. Brenan, M. and Rees, D.J. (1997) Sequence analysis of rat integrin alpha E1 and alpha E2 subunits: tissue expression reveals plenotypic similarities between intraepithelial lymphocytes and dendritic cells in lymph.Eur. J. Immunol. 27: 3070-3079. 3. Kostulas, N. et al. (2002) Dendritic cells are present in ischemic brain after permanent middle cerebral artery occlusion in the rat. Stroke. 33: 1129-1134. 4. Rival, C. et al. (2006) Identification of a dendritic cell population in normal testis and in chronically inflamed testis of rats with autoimmune orchitis. Cell Tissue Res. 324: 311-318 5. Tsuchiya, T. et al. (2002) Dendritic cell involvement in pulmonary granuloma formation elicited by bacillus calmette-guerin in rats. Am. J. Respir. Crit. Care Med. 165: 1640-1646. 6. Zilka, N. et al. (2009) Human misfolded truncated tau protein promotes activation of microglia and leukocyte infiltration in the transgenic rat model of tauopathy.J. Neuroimmunol. 209: 16-25. 7. Schwartzkopff, J. et al. (2010) NK cell depletion delays corneal allograft rejection in baby rats.Mol. Vis. 16: 1928-1935. 8. Baca Jones, C.C. et al. (2009) Rat cytomegalovirus infection depletes MHC II in bone marrow derived dendritic cells.Virology. 388: 78-90. 9. Zhou. Y.J. et al. (2010) The role of the lactadherin in promoting intestinal DCs development in vivo and vitro.Clin Dev Immunol.2010: 357541. 10. Aiello, S. et al. (2000) Thymic Dendritic Cells Express Inducible Nitric Oxide Synthase and Generate Nitric Oxide in Response to Self- and AlloantigensJ Immunol. 164: 4649-58. 11. Camelo, S. et al. (2003) Local retention of soluble antigen by potential antigen-presenting cells in the anterior segment of the eye.Invest Ophthalmol Vis Sci. 44: 5212-9. 12. Camelo, S. et al. (2004) The distribution of antigen in lymphoid tissues following its injection into the anterior chamber of the rat eye.J Immunol. 172: 5388-95. 13. Henry, F. et al. (1999) Antigen-presenting cells that phagocytose apoptotic tumor-derived cells are potent tumor vaccines.Cancer Res. 59: 3329-32. 14. Liu, L. et al. (1998) Dendritic cell heterogeneity in vivo: two functionally different dendritic cell populations in rat intestinal lymph can be distinguished by CD4 expression.J Immunol. 161: 1146-55. 15. O'Sullivan, N.L. et al. (2001) Lymphocyte lineages at mucosal effector sites: rat salivary glands.J Immunol. 166: 5522-9. 16. Penttila, I.A. et al. (2003) Maternal milk regulation of cell infiltration and interleukin 18 in the intestine of suckling rat pups.Gut. 52: 1579-86. 17. Stephens, L.A. et al. (2004) Phenotypic characterization of regulatory CD4+CD25+ T cells in rats.Int Immunol. 16: 365-75. 18. Sugawara, I. et al. (2004) Pathological and immunological profiles of rat tuberculosis.Int J Exp Pathol. 85: 125-34. 19. Tiurbe, G. et al. (2009) Inhibitory effects of rat bone marrow-derived dendritic cells on naïve and alloantigen-specific CD4+ T cells: a comparison between dendritic cells generated with GM-CSF plus IL-4 and dendritic cells generated with GM-CSF plus IL-10.BMC Res Notes. 2: 12. 20. Tsuchiya, T. et al. (2002) Dendritic cell involvement in pulmonary granuloma formation elicited by bacillus calmette-guérin in rats.Am J Respir Crit Care Med. 165: 1640-6.
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