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>   home   >   Products   >   Primary Antibodies   >   Metabolism   >   Anti-Human Myeloperoxidase Antibody, clone 2C7 (RPE)   

Anti-Human Myeloperoxidase Antibody, clone 2C7

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human Myeloperoxidase Antibody, clone 2C7  ABD12111
    Staining of human peripheral blood granulocytes with FITC conjugated Mouse anti Human myeloperoxidase following permeabilisation with Leucoperm
  • FC - Anti-Human Myeloperoxidase Antibody, clone 2C7  ABD12111
    Staining of human peripheral blood granulocytes with Mouse anti Human myeloperoxidase following permeabilisation with Leucoperm
  • IHC-P - Anti-Human Myeloperoxidase Antibody, clone 2C7  ABD12111
    Staining of human bone marrow. Formalin fixed, paraffin processed tissue with Mouse anti Human Myeloperoxidase
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05164
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 2C7
Calculated MW 83869 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Human myeloperoxidase.
Shelf Life 18 months from date of despatch.
Gene ID 4353
Other Names Myeloperoxidase, MPO,, Myeloperoxidase, 89 kDa myeloperoxidase, 84 kDa myeloperoxidase, Myeloperoxidase light chain, Myeloperoxidase heavy chain, MPO
Target/Specificity Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes human myeloperoxidase (MPO). MPO is an important component of azurophilic granules in neutrophils, being involved in microbicidal processes. The protein is a multimer of 2 heavy chains (55kD) and two light chains (15kD), the heavy chains being linked by a disulphide bond. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 recognizes native MPO in Western blots, and the heavy chain following boiling of the sample. Mouse anti-Human Myeloperoxidase antibody, clone 2C7 also recognizes recombinant MPO in Western blots and weakly in ELISA.Mouse anti-Human Myeloperoxidase antibody, clone 2C7 may be of value in the study of myeloid cells and myeloid leukaemias by flow cytometry following cell permeablisation.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human Myeloperoxidase Antibody, clone 2C7 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Audrain, M.A.P. et al. (1997) Anti-native and recombinant myeloperoxidase monoclonals and human autoantibodies.
Clin. Exp. Immunol. 107: 127-134. 2. Patry, Y.C. et al. (1997) Difference in antigenic determinant profiles between human and rat myeloperoxidase.
Clin ExpImmunol. 132: 505-8. 3. Zhang, N. et al. (2008) Different types of T-effector cells orchestrate mucosal inflammation in chronic sinus disease.
J Allergy Clin Immunol. 122: 961-8. 4. Sloane, A.J. et al. (2005) Proteomic analysis of sputum from adults and children with cystic fibrosis and from control subjects.
Am J Respir Crit Care Med. 172: 1416-26. 5. Luo, B. et al. (2013) Immunopathology features of chronic rhinosinusitis in high-altitude dwelling Tibetans.
Allergy Rhinol (Providence). 4: e69-76. 6. Behnen, M. et al. (2014) Immobilized immune complexes induce neutrophil extracellular trap release by human neutrophil granulocytes via Fc?RIIIB and Mac-1.
J Immunol. 193 (4): 1954-65. 7. Villiers, E. et al. (2006) Identification of acute myeloid leukemia in dogs using flow cytometry with myeloperoxidase, MAC387, and a canine neutrophil-specific antibody.
Vet Clin Pathol. 35 (1): 55-71.

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Cat# ABD12111
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