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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti-Tubulin beta 3 Antibody, clone TU-20 (FITC)   

Anti-Tubulin beta 3 Antibody, clone TU-20

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q13509
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names TU-20
Calculated MW 50433 Da
Additional Information
Other Species M,Baboon,Rat,Ha,Pig,B
Purification Purified IgG prepared by DEAE chromatography
Immunogen Synthetic peptide, ESESQGPK, corresponding to amino acids 441-448 of human class III beta tubulin coupled to Keyhole Limpet Hemocyanin (KLH).This sequence is conserved across all species.
Shelf Life 18 months from date of despatch.
Gene ID 10381
Other Names Tubulin beta-3 chain, Tubulin beta-4 chain, Tubulin beta-III, TUBB3, TUBB4
Target/Specificity Mouse anti-Tubulin beta 3 antibody, clone TU-20 recognizes class III beta-tubulin which is reported to be restricted to neuronal tissue.Mouse anti-Tubulin beta 3 antibody, clone TU-20 has been used to investigate tumors of neuronal origin including neuroblastoma and ganglioneuroma. Class III beta tubulin has not been detected in tumors of non neuronal origin.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Tubulin beta 3 Antibody, clone TU-20 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Draberova, E. et al. (1998) Expression of class III beta-tubulin in normal and neoplastic human tissues.
Histochem. Cell Biol. 109: 231-239. 2. Hattermann, K. et al. (2010) The chemokine receptor CXCR7 is highly expressed in human glioma cells and mediates antiapoptotic effects.
Cancer Res. 70: 3299-308. 3. Rosito, M. et al. (2012) CXCL16 Orchestrates Adenosine A3 Receptor and MCP-1/CCL2 Activity to Protect Neurons from Excitotoxic Cell Death in the CNS.
J Neurosci. 32: 3154-63. 4. Nicot, A. and DiCicco-Bloom, E. (2001) Regulation of neuroblast mitosis is determined by PACAP receptor isoform expression.
Proc Natl Acad Sci U S A. 98: 4758-63. 5. Peknicová, J. et al. (2001) Differential subcellular distribution of tubulin epitopes in boar spermatozoa: recognition of class III beta-tubulin epitope in sperm tail.
Biol Reprod. 65: 672-9. 6. Huang, C.L. et al. (2010) Expression of ERCC1 and class III ß-tubulin is associated with the survival of resected stage III non-small cell lung cancer patients treated with induction chemoradiotherapy using carboplatin-taxane.
Exp Ther Med. 1: 445-51.

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Cat# ABD12151
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