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>   home   >   Products   >   Primary Antibodies   >   CD8 alpha Antibody, clone 11-39 (Monoclonal Antibody) (RPE)   

CD8 alpha Antibody, clone 11-39 (Monoclonal Antibody) (FITC)

Mouse Anti-Chicken Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Chicken
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 11-39
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Chicken T-cells.
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti-chicken CD8 alpha, clone 11-39 recognizes the alpha chain of the chicken CD8 homologue, a 33-35kD cell surface protein. CD8 is expressed as either alpha/alpha homodimers or alpha/beta heterodimers on a subpopulation of T cells and NK cells. Mouse anti-chicken CD8 alpha, clone 11-39 recognises all polymorphic forms of chicken CD8 alpha. Mouse anti-chicken CD8 alpha, clone 11-39 has been demonstrated to cross react with Turkey (Liet al.1999).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3); 1% Bovine Serum Albumin
Storage Store at +4℃ or -20℃.
PrecautionsCD8 alpha Antibody, clone 11-39 (Monoclonal Antibody) (FITC) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Luhtala, M. et al. (1995) Characterization of chicken CD8-specific monoclonal antibodies recognizing novel epitopes.
Scand J Immunol. 42 (1): 171-4. 2. Luhtala, M et al. (1997) Polymorphism of chicken CD8- alpha, but not CD8-beta.
Immunogenetics. 46: 396 - 401. 3. Li, Z., et al (1999) Cross-Reactive Anti-Chicken CD4 and CD8 Monoclonal Antibodies Suggest Polymorphism of the Turkey CD8a Molecule
Poultry Science 78:1526-1531 4. McKenna, G.F. (2003) Immunopathologic investigations with an attenuated chicken anemia virus in day-old chickens.
Avian Dis. 47: 1339-45. 5. Morimura, T. et al. (1996) Apoptosis and CD8-down-regulation in the thymus of chickens infected with Marek's disease virus.
Arch Virol. 141 (11): 2243-9. 6. Luhtala M (1998) Chicken CD4, CD8alphabeta, and CD8alphaalpha T cell co-receptor molecules.
Poult Sci. 77 (12): 1858-73. 7. Imhof, B.A. et al. (2000) Intestinal CD8 alpha alpha and CD8 alpha beta intraepithelial lymphocytes are thymus derived and exhibit subtle differences in TCR beta repertoires.
J Immunol. 165 (12): 6716-22. 8. Arstila, T.P. & Lassila, O. (1993) Androgen-induced expression of the peripheral blood gamma delta T cell population in the chicken.
J Immunol. 151 (12): 6627-33. 9. Bohls, R.L. et al. (2006) The use of flow cytometry to discriminate avian lymphocytes from contaminating thrombocytes.
Dev Comp Immunol. 30 (9): 843-50. 10. Powell, F.L. et al. (2009) The turkey, compared to the chicken, fails to mount an effective early immune response to Histomonas meleagridis in the gut.
Parasite Immunol. 31 (6): 312-27. 11. Katevuo, K & Vainio, O. (1996) Thymocyte emigration in the chicken: an over-representation of CD4+ cells over CD8+ in the periphery.
Immunology. 89 (3): 419-23. 12. Morimura, T. et al. (1995) Immunomodulation of peripheral T cells in chickens infected with Marek's disease virus: involvement in immunosuppression.
J Gen Virol. 76 ( Pt 12): 2979-85. 13. Powell, F. et al. (2009) Development of reagents to study the turkey's immune response: Identification and molecular cloning of turkey CD4, CD8α and CD28.
Dev Comp Immunol. 33 (4): 540-6. 14. Juul-Madsen, H.R. et al. (2002) Major histocompatibility complex-linked immune response of young chickens vaccinated with an attenuated live infectious bursal disease virus vaccine followed by an infection.
Poult Sci. 81 (5): 649-56. 15. Wang, Y. et al. (2003) A novel method to analyze viral antigen-specific cytolytic activity in the chicken utilizing flow cytometry.
Vet Immunol Immunopathol. 95 (1-2): 1-9. 16. Arstila, T.P. et al. (1995) Primed avian γδ T cells respond to mycobacterial antigens, but show no preference for the 65-kDa heat shock protein.
Cell Immunol. 162 (1): 74-9. 17. Arstila, T.P. et al. (1994) γδ and αβ T cells are equally susceptible to apoptosis.
Scand J Immunol. 40 (2): 209-15. 18. Rosa, A.C. et al. (2014) Isolation and molecular characterization of Brazilian turkey reovirus from immunosuppressed young poults.
Arch Virol. 159 (6): 1453-7.

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