|Application ||IHC-F, FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant|
|Immunogen||Splenocytes from ATL mice.|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti-Sheep MHC class II antibody, clone 37.68 recognises a monomorphic epitope on ovine MHC class II DR molecules, constitutively expressed on antigen presenting cells such as dendritic cells, B lymphocytes, monocytes, macrophages, activated T lymphocytes and may be induced on a range of other cell types by interferon gamma.The major histocompatibility complex (MHC) is a cluster of genes some of which are important in the immune response to infections. In sheep, this complex is referred to as the ovine leukocyte antigen (OLA) region. There are 2 major types of MHC class IIa molecules encoded by the OLA which are DR and DQ each composed of an alpha and beta chain.|
|Preservative & Stabilisers||0.09% Sodium Azide|
|Storage||Store at +4℃ or at -20 ℃.|
|Precautions||Anti-Sheep MHC Class II DR Monomorphic Antibody, clone 37.68 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Puri, N. et al. (1985) Sheep lymphocyte antigens (OLA) II. Major histocompatibility complex class II molecules. Immunology. 56: 725 - 733. 2. Puri, N. et al. (1987) Monoclonal antibodies to sheep MHC class I and class II molecules: biochemical characterization of three class I gene products and four distinct subpopulations of class II molecules. Vet. Immunol. Immunopathol. 15: 59 - 86. 3. Puri, N. et al. (1987) Sheep MHC class II molecules. II. Identification and characterization of four distinct subsets of sheep MHC class II molecule. Immunology. 62: 575 - 580. 4. Puri, N. et al. (1987) Monoclonal antibodies to sheep MHC class II molecules recognize all HLA-D or subsets of HLA-D region products. Hum. Imunol. 20: 195 - 207. 5. Ballingall. K. et al. (1995) Analysis of the fine specificities of sheep major histocompatatibility complex class II - specific monoclonal antibodies using mouse L - cell transfectants.Anim. Genet. 26: 79-84.
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