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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD62P Antibody, clone Psel.KO.2.12 (RPE)   

Anti-Human CD62P Antibody, clone Psel.KO.2.12

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD62P Antibody, clone Psel.KO.2.12  ABD12266
    Staining of thrombin activated platelets with Mouse anti Human CD62P:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P16109
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names Psel.KO.2.12
Calculated MW 90834 Da
Additional Information
Other Species Ga,Rat,Sh
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen CD62P transfected 300.19 cells.
Shelf Life 12 months from date of reconstitution.
Gene ID 6403
Other Names P-selectin, CD62 antigen-like family member P, Granule membrane protein 140, GMP-140, Leukocyte-endothelial cell adhesion molecule 3, LECAM3, Platelet activation dependent granule-external membrane protein, PADGEM, CD62P, SELP, GMRP, GRMP
Target/Specificity Mouse anti-Human CD62P antibody, clone Psel.KO.2.12 recognizes the CD62P cell surface antigen, a 140kD glycoprotein also known as P-selectin.CD62P is expressed by activated platelets and endothelial cells, and plays an important role in adhesive processes between leucocytes and endothelial cells. Clone Psel.KO.2.12 is reported to inhibit P-selectin-dependent adhesion between HL60 cells and P-selectin transfected COS cells (Massagueret al.2000).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Human CD62P Antibody, clone Psel.KO.2.12 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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1. Massaguer, A. et al. (2000) Production and characterization of monoclonal antibodies against conserved epitopes of P-selectin (CD62P).
Tissue Antigens. 56 (2): 117-28. 2. Massaguer, A. et al. (2003) Characterization of platelet and soluble-porcine P-selectin (CD62P).
Vet Immunol Immunopathol. 96 (3-4): 169-81. 3. Massaguer, A. et al. (2002) Reactivity of CD62P workshop mAbs with resting and activated platelets from different animal species.
In: Leucocyte Typing VII. Edited by Mason, D. et al. Oxford University Press, pp 342-343. 4. Major, T.C. et al. (2010) The attenuation of platelet and monocyte activation in a rabbit model of extracorporeal circulation by a nitric oxide releasing polymer.
Biomaterials. 31: 2736-45. 5. Johnson, C.A. Jr. et al. (2008) Flow cytometric assays for quantifying activated ovine platelets.
Artif Organs. 32: 136-45. 6. Johnson, C.A. Jr. et al. (2011) Platelet activation in ovines undergoing sham surgery or implant of the second generation PediaFlow pediatric ventricular assist device.
Artif Organs. 35 (6): 602-13. 7. Johnson, C.A. Jr. et al. (2011) Biocompatibility assessment of the first generation PediaFlow pediatric ventricular assist device.
Artif Organs. 35 (1): 9-21. 8. Dasse, K.A. et al. (2007) Assessment of hydraulic performance and biocompatibility of a MagLev centrifugal pump system designed for pediatric cardiac or cardiopulmonary support.
ASAIO J. 53 (6): 771-7. 9. Ding, J. et al. (2015) Quantification of Shear-Induced Platelet Activation: High Shear Stresses for Short Exposure Time.
Artif Organs. 39 (7): 576-83. 10. Tran GT et al. (2010) Membrane attack complex of complement is not essential for immune mediated demyelination in experimental autoimmune neuritis.
J Neuroimmunol. 229 (1-2): 98-106.

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Cat# ABD12266
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