Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Primary Antibodies   >   Anti-Bovine CD45RO Antibody, clone IL-A116 (RPE)   

Anti-Bovine CD45RO Antibody, clone IL-A116

Mouse Anti-Bovine Monoclonal Antibody

  • FC - Anti-Bovine CD45RO Antibody, clone IL-A116  ABD12269
    Staining of bovine peripheral blood lymphocytes with Mouse anti Bovine CD45RO:RPE
  • FC - Anti-Bovine CD45RO Antibody, clone IL-A116  ABD12269
    Staining of bovine peripheral blood lymphocytes with Mouse anti Bovine CD45RO followed by Goat anti Mouse IgG:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Bovine
Host Mouse
Clonality Monoclonal
Isotype IgG3
Clone Names IL-A116
Additional Information
Other Species Ga
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Bovine peripheral blood monouclear cells.
Shelf Life 12 months from date of reconstitution.
Target/Specificity Mouse anti-Bovine CD45RO, clone IL-A116, specifically recognises the bovine homologue of the human CD45RO cell surface antigen.CD45, also known as Leucocyte Common Antigen or LCA, occurs in a number of isoforms, clone IL-A116 is specific for the low molecular weight isoform termed CD45RO, the isoform associated with expression on memory T-cells. Bovine CD45RO is expressed by monocytes, granulocytes and subsets of thymocytes, CD4+ T cells and CD8+ T cells. Studies utilizing clone IL-A116 have demonstrated that the percentage of CD45RO+CD8+ T cells increase from approximately 5% in neonatal calves to approximately 35% in adult cattle over the age of 5 years (Hogget al.2011). It has been demonstrated that mouse anti-bovine CD45RO, clone IL-A116 immunoprecipitates a molecule of 180kDa (Bembridgeet al1995) which is analogus to the molecular weight of human and mouse CD45RO.Clone IL-A116 has been demonstrated to recognise the CD45RO cell surface antigen by flow cytometry in both European cattle, Bos taurus, and in Zebu, B.indicus(Bembridgeet al1995).
Preservative & Stabilisers 0.09% Sodium Azide
Storage Storage at 4℃ or at -20℃.
PrecautionsAnti-Bovine CD45RO Antibody, clone IL-A116 is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abgent antibody to, and receive a free "I Love Antibodies" mug.


1. Bembridge, al. (1995) CD45RO expression on bovine T cells: relation to biological function.
Immunology 86: 537-544. 2. Hogg A.E. et. al. (2011) Characterization of age-related changes in bovine CD8+ T-cells
Vet. Immunol. Immunopath. 140:47-54 3. Whelan A.O. et. al. (2011) Development of an Antibody to Bovine IL-2 Reveals Multifunctional CD4 TEM Cells in Cattle Naturally Infected with Bovine Tuberculosis
PLoS ONE 6(12): e29194. doi:10.1371/journal.pone.0029194 4. Howard, C.J. et al. (1993) Summary of workshop findings for cattle (Tables 1 and 2).
Vet Immunol. Immunopathol. 39:25-48. 5. Sopp, P. et al. (2001) IFN gamma and IL-4 production by CD4, CD8 and WC1 gamma delta TCR+ T cells from cattle lymph nodes and blood.
Vet. Immunol. Immunopathol. 81: 85-96. 6. McInnes, al. (1999) Phenotypic analysis of local cellular responses in calves infected with bovine respiratory syncytial virus.
Immunology 96: 396-403 7. Bembridge, G.P. et al. (1993) Comparison of monoclonal antibodies with potential specificity for restricted isoforms of the leukocyte common antigen (CD45R).
Vet. Immunol. Immunopathol. 39:129-136. 8. Naessens, J. et al. (1993) Cross-reactivity of workshop antibodies with cells from domestic and wild ruminants.
Vet. Immunol. Immunopathol. 39: 283-290.

Abgent welcomes feedback from its customers.

If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# ABD12269
Availability: Inquire
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abgent, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions