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>   home   >   Products   >   Primary Antibodies   >   Immunology   >   Anti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12 (RPE)   

Anti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12  ABD12306
    Staining of J774 cells with Rat anti Mouse TREM-1:Alexa Fluor® ?647
  • FC - Anti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12  ABD12306
    Staining of J774 cells with Rat anti Mouse TREM-1:Alexa Fluor® 488
  • FC - Anti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12  ABD12306
    Staining of J774 cells with Rat anti Mouse TREM-1:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9JKE2
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names L5-B8.2A12.3A12
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Mouse TREM-1 Fc fusion protein
Shelf Life 18 months from date of despatch.
Other Names Triggering receptor expressed on myeloid cells 1, TREM-1, CD354, Trem1
Target/Specificity Rat anti-Mouse Trem-1 antibody, clone L5-B8.2A12.3A12 recognizes mouse triggering receptor expressed on myeloid cells 1 (TREM-1), a 30kD member of the immunoglobulin superfamily expressed on neutrophils and a subset of monocytes. TREM-1 is involved in the microbial inflammatory response. It acts in conjunction with the adaptor protein DAP12 to activate neutrophils and monocytes, leading to the secretion of pro-inflammatory mediators and enhancement of the inflammatory response. Microbial infection also induces the release of soluble form of TREM-1 from monocytes, which is reported to act as an inhibitor of TREM-1. TREM-1 mediates the septic shock pathway, and blocking TREM-1 has been reported to reduce inflammation and increase survival in certain models of bacterial infection.
Preservative & Stabilisers 0.09% Sodium Azide
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse Trem-1 Antibody, clone L5-B8.2A12.3A12 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12306
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