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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti-Human CD59 Antibody, clone MEM-43/5    

Anti-Human CD59 Antibody, clone MEM-43/5 (RPE)

Mouse Anti-Human Monoclonal Antibody

  • FC - Anti-Human CD59 Antibody, clone MEM-43/5 (RPE) ABD12347
    Staining of KG1 cells with Mouse anti Human CD59
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P13987
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names MEM-43/5
Calculated MW 14177 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein A
Shelf Life 18 months from date of despatch.
Gene ID 966
Other Names CD59 glycoprotein, 1F5 antigen, 20 kDa homologous restriction factor, HRF-20, HRF20, MAC-inhibitory protein, MAC-IP, MEM43 antigen, Membrane attack complex inhibition factor, MACIF, Membrane inhibitor of reactive lysis, MIRL, Protectin, CD59, CD59, MIC11, MIN1, MIN2, MIN3, MSK21
Target/Specificity Mouse anti-Human CD59 antibody, clone MEM-43/5 reacts with a PI-linked glycoprotein, Mw 18-20kDa found on all types of leucocytes including platelets. The antigen is expressed on many haemopoietic and non-haemopoietic cells. Mouse anti-Human CD59 antibody, clone MEM-43/5 recognizes an epitope distinct to that bound by clone MEM-43.
Preservative & Stabilisers 0.09% Sodium azide; Stabilising agent
Storage Storage at +4ºC. DO NOT FREEZE.
PrecautionsAnti-Human CD59 Antibody, clone MEM-43/5 (RPE) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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1. Stefanova, I. et al. (1989) Characterization of a broadly expressed human leucocyte surface antigen MEM-43 anchored in membrane through phosphatidylinositol
Mol. Immunol. 26: 153-161. 1. Stefanova, I., et al. (1989) in Leucocyte Typing IV: White cell differentiation antigens.
Ed. Knapp, W. et al. Oxford University Press pp 678-697. 3. Tandon, N. et al. (1994) Expression and function of multiple regulators of complement activation in autoimmune thyroid disease.
Immunology 81: 643-647. 4. Horejsi, V. et al. (1988) Monoclonal antibodies against human leucocyte antigens. II. Antibodies against CD45 (T200), CD3 (T3), CD43, CD10 (CALLA), transferrin receptor (T9), a novel broadly expressed 18-kDa antigen (MEM-43) and a novel antigen of restricted expression (MEM-74).
Fol. Bio. (Prague) 34: 23-24. 5. Ellison, B.S. et al. (2007) Complement susceptibility in glutamine deprived breast cancer cells.
Cell Div. 2: 20. 6. Vanderplasschen, A. et al. (1998) Extracellular enveloped vaccinia virus is resistant to complement because of incorporation of host complement control proteins into its envelope.
Proc Natl Acad Sci U S A. 95: 7544-9. 7. Takemoto, M. et al. (2007) Human herpesvirus 7 infection increases the expression levels of CD46 and CD59 in target cells.
J Gen Virol. 88: 1415-22. 8. Ohyama, M. et al. (2006) Characterization and isolation of stem cell-enriched human hair follicle bulge cells.
J Clin Invest. 116: 249-60.

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Cat# ABD12347
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