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>   home   >   Products   >   Primary Antibodies   >   Anti-Mouse CD200 Antibody, clone OX-90 (RPE)   

Anti-Mouse CD200 Antibody, clone OX-90 (Biotin)

Rat Anti-Mouse Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession O54901
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2a
Clone Names OX-90
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G from tissue culture supernatant
Immunogen Mouse CD200-rat CD4 fusion protein.
Shelf Life 18 months from date of despatch.
Other Names OX-2 membrane glycoprotein, MRC OX-2 antigen, CD200, Cd200, Mox2
Target/Specificity Rat anti-Mouse CD200 antibody, clone OX-90 recognizes the mouse CD200 cell surface antigen, also known as OX2.CD200 is expressed by splenic B lymphocytes, follicular dendritic cells, splenic endothelium and by neurons.Studies have suggested that the CD200 - CD200 ligand system is of importance in the control of macrophage and granulocyte activation.
Preservative & Stabilisers 0.09% Sodium Azide; 1% Bovine Serum Albumin
Storage Store at +4℃ or at -20 ℃.
PrecautionsAnti-Mouse CD200 Antibody, clone OX-90 (Biotin) is for research use only and not for use in diagnostic or therapeutic procedures.
Citations (0)

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1. Hoek, R.M. et al. (2000) Down-regulation of the macrophage lineage through interaction with OX2 (CD200).
Science. 290 (5497): 1768-71. 2. Nathan, C. & Muller, W.A. (2001) Putting the brakes on innate immunity: a regulatory role for CD200?
Nat Immunol. 2 (1): 17-9. 3. Broderick, C. et al. (2002) Constitutive retinal CD200 expression regulates resident microglia and activation state of inflammatory cells during experimental autoimmune uveoretinitis.
Am J Pathol. 161 (5): 1669-77. 4. Seeds, R.E. et al. (2011) The role of myeloid receptors on murine plasmacytoid dendritic cells in induction of type I interferon.
Int Immunopharmacol. 11 (7): 794-801. 5. Burger, P.E. et al. (2009) High aldehyde dehydrogenase activity: a novel functional marker of murine prostate stem/progenitor cells.
Stem Cells. 27: 2220-8. 6. Garza, L.A. et al. (2011) Bald scalp in men with androgenetic alopecia retains hair follicle stem cells but lacks CD200-rich and CD34-positive hair follicle progenitor cells.
J Clin Invest. 121: 613-22. 7. Ko, Y.C. et al (2009) Endothelial CD200 is heterogeneously distributed, regulated and involved in immune cell-endothelium interactions.
J Anat. 214: 183-95. 8. Koning, N. et al. (2009) Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions.
J Neuropathol Exp Neurol. 68: 159-67. 9. Krejsek, J. et al (2010) Expression of CD200/CD200R regulatory molecules on granulocytes and monocytes is modulated by cardiac surgical operation.
Perfusion. 25: 389-97. 10. Rijkers, E.S. (2007) Ligation of CD200R by CD200 is not required for normal murine myelopoiesis.
Eur J Haematol. 79: 410-6. 11. Rijkers, E.S. et al. (2008) The inhibitory CD200R is differentially expressed on human and mouse T and B lymphocytes.
Mol Immunol. 45: 1126-35.

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Cat# ABD12355
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