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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Prostate Specific Membrane Antigen Antibody, clone GCP-04    

Anti Prostate Specific Membrane Antigen Antibody, clone GCP-04

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q04609
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names GCP-04
Calculated MW 84331 Da
Additional Information
Other Species Rat,Pig
Purification Purified IgG prepared by affinity chromatography on Protein A
Immunogen Recombinant fragment corresponding to amino acids 44-750 of human GCPII.
Shelf Life 18 months from date of despatch.
Gene ID 2346
Other Names Glutamate carboxypeptidase 2,, Cell growth-inhibiting gene 27 protein, Folate hydrolase 1, Folylpoly-gamma-glutamate carboxypeptidase, FGCP, Glutamate carboxypeptidase II, GCPII, Membrane glutamate carboxypeptidase, mGCP, N-acetylated-alpha-linked acidic dipeptidase I, NAALADase I, Prostate-specific membrane antigen, PSM, PSMA, Pteroylpoly-gamma-glutamate carboxypeptidase, FOLH1, FOLH, NAALAD1, PSM, PSMA
Target/Specificity Mouse anti prostate specific Membrane Antigen antibody, clone GCP-04 recognises amino acids 100-104 of the extracellular domain of prostate specific membrane antigen (PSMA), otherwise known as GCPII (glutamate carboxypeptidase II), a 95-110kDa type II transmembrane glycoprotein and member of the peptidase M28 family. Nomenclature for GCPII is dependent upon tissue specificity. PSMA is assigned to GCPII of prostate origin which is up-regulated in prostate cancer and a reliable diagnostic marker. Folate hydrolase (FOLH1) describes GCPII in the intestine and is required for folate uptake, whilst NAALADase refers to GCPII expressed in the central nervous system, which acts to cleave N-acetylaspartylglutamate (NAAG) to release glutamate, implicated in pathological conditions including Alzheimer’s and Huntington’s disease.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Prostate Specific Membrane Antigen Antibody, clone GCP-04 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12493
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