|Application ||IHC-F, IF, FC, IP|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Rat Spleen cell homogenate|
|Shelf Life||18 months from date of despatch.|
|Target/Specificity||Mouse anti rat CD169 antibody, clone ED3 recognises the rat CD169 cell surface antigen, a ~185 kDa molecule expressed by macrophages, predominately confined to lymphoid organs only. Monocytes and granulocytes are negative. No other cell types are positive. The most conspicious property of ED3 is it stains marginal zone macrophages and marginal metallophils in the spleen very strongly. Furthermore, macrophages in (auto-immune) diseased tissues express the ED3 antigen. In healthy tissue no expression occurs. CD169 is a receptor for glycoconjugates containing sialic acid.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat CD169 Antibody, clone ED3 is for research use only and not for use in diagnostic or therapeutic procedures.|
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