|Application ||IHC-F, FC, IP|
|Calculated MW||51438 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||MLR generated rat T cells.|
|Shelf Life||18 months from date of despatch.|
|Other Names||T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3, W3/25 antigen, CD4, Cd4|
|Target/Specificity||Mouse anti Rat CD4 (Domain 1) antibody, clone OX-38 recognizes the rat CD4 cell surface antigen, also known as W3/25 antigen or T-cell surface antigen T4/Leu-3. CD4 is a 430 amino acid ~55 kDa single pass type I transmembrane glycoprotein expressed by T helper cells, monocytes and macrophages.Clone OX-38 competes for binding with clone W3/25.Mouse anti Rat CD4 (Domain 1) antibody, clone OX-38 has been utilized successfully for the in vitro depletion of T helper cells from slice cultures in studies looking at myelin loss in multiple sclerosis, the observed disruption being abrogated in these experimental conditions by T-cell depletion (Pusicet al.2015).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Rat CD4 (Domain 1) Antibody, clone OX-38 is for research use only and not for use in diagnostic or therapeutic procedures.|
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