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>   home   >   Products   >   Primary Antibodies   >   Anti Rat CD252 Antibody, clone ATM-2    

Anti Rat CD252 Antibody, clone ATM-2

Mouse Anti-Rat Monoclonal Antibody

  • FC - Anti Rat CD252 Antibody, clone ATM-2  ABD12555
    LPS stimulated rat splenocytes stained with Mouse anti Rat CD252:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Z2P3
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names ATM-2
Calculated MW 22190 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen ACI-S1 rat T-cell lymphoma cell line.
Shelf Life 18 months from the date of despatch
Gene ID 89814
Other Names Tumor necrosis factor ligand superfamily member 4, OX40 ligand, OX40L, CD252, Tnfsf4, Ox40l, Txgp1
Target/Specificity Mouse anti Rat CD252 antibody, clone ATM-2 specifically recognizes rat CD252, otherwise known as OX40L or CD134L, a ~22 kDa type II transmembrane glycoprotein and member of the TNF superfamily, expressed by antigen-presenting cells including activated dendritic cells and B cells, and also by vascular endothelium. The interaction of CD252 with its receptor OX40/CD134, acts as a co-stimulator of T cell activation, proliferation and both Th1 and Th2 cytokine production, and is also important in activated B cell proliferation and secretion of immunoglobulins (Igs). CD252/OX40 interaction has been implicated in HTLV-1 associated diseases including myelopathy and adult T cell leukaemia, and also with the autoimmune diseases rheumatoid arthritis and inflammatory bowel disease. Mouse anti Rat CD252 antibody, clone ATM-2 has been shown to block the co-stimulatory activity of CD252 on rat T cell proliferation.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred
PrecautionsAnti Rat CD252 Antibody, clone ATM-2 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12555
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