|Application ||IHC-P, IHC-F, FC, IP|
|Calculated MW||144837 Da|
|Purification||Purified IgG prepared by affinity chromatography|
|Immunogen||Cloned mouse Th2 cell lines.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Receptor-type tyrosine-protein phosphatase C, 188.8.131.52, Leukocyte common antigen, L-CA, Lymphocyte antigen 5, Ly-5, T200, CD45, Ptprc, Ly-5|
|Target/Specificity||Rat anti Mouse CD45RB antibody, clone C363-16A recognises an isoform of CD45 called CD45RB. CD45 is a member of the protein tyrosine phosphatase (PTP) family. The PTP proteins are signalling molecules that are involved in a variety of cellular processes including cell growth, differentiation, mitosis and oncogenesis. CD45 is an essential regulator of T- and B-cell antigen receptor signalling.CD45 has various isoforms generated by different splicing of exons. Clone C363-16A recognises CD45RB, generated by exon 5 splicing. This 220kDa glycoprotein is expressed on peripheral B-cells, naïve T-cells, thymocytes, macrophages and dendritic cells.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Mouse CD45RB Antibody, clone C363-16A is for research use only and not for use in diagnostic or therapeutic procedures.|
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