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>   home   >   Products   >   Primary Antibodies   >   Antibody Collections   >   Amyotrophic Lateral Sclerosis (ALS)   >   Anti Rat Neurofilament M (C-Terminal) Antibody, clone 3H11    

Anti Rat Neurofilament M (C-Terminal) Antibody, clone 3H11

Mouse Anti-Rat Monoclonal Antibody

  • WB - Anti Rat Neurofilament M (C-Terminal) Antibody, clone 3H11  ABD12641
    Western blot of rat cortex lysate showing specific immunolabeling of the ~145 kDa NF-M protein
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P12839
Other Accession P16053, P08553, P07197
Reactivity Rat
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names 3H11
Calculated MW 95791 Da
Additional Information
Other Species H,M,C,B
Immunogen Recombinant fusion protein containing the extreme C-terminus of rat NF-M expressed in and purified from E.coli.
Shelf Life 18 months from date of despatch.
Gene ID 24588
Other Names Neurofilament medium polypeptide, NF-M, 160 kDa neurofilament protein, Neurofilament 3, Neurofilament triplet M protein, Nefm, Nef3, Nfm
Target/Specificity Mouse anti Rat Neurofilament M antibody, clone 3H11 recognizes the carboxy terminus of rat neurofilament M (NF-M), one of three neurofilament proteins (NF-H, NF-M and NF-L). Neurofilaments are 10nm intermediate filaments found in neurons, with especially high concentrations along the axons, where they appear to control axonal diameter. It is thought that phosphorylation of NF-M results in the formation of interfilament cross-bridges that are important in the maintenance of axonal calibre.Mouse anti Rat Neurofilament M antibody, clone 3H11 also binds to a C- terminal epitope of bovine NF-M.
Preservative & Stabilisers 0.065% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Rat Neurofilament M (C-Terminal) Antibody, clone 3H11 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12641
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