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>   home   >   Products   >   Primary Antibodies   >   Stem Cells   >   Anti Mouse CD276 Antibody, clone MJ8    

Anti Mouse CD276 Antibody, clone MJ8

Rat Anti-Mouse Monoclonal Antibody

  • FC - Anti Mouse CD276 Antibody, clone MJ8  ABD12696
    Mouse CD276 transfected cells stained witth Rat anti Mouse CD276:FITC
  • FC - Anti Mouse CD276 Antibody, clone MJ8  ABD12696
    Mouse CD276 transfected cells stained witth Rat anti Mouse CD276:RPE
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q8VE98
Reactivity Mouse
Host Rat
Clonality Monoclonal
Isotype IgG2b
Clone Names MJ8
Calculated MW 34001 Da
Additional Information
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Mouse IgG2a Fc-CD276 (aa 1-242).
Shelf Life 18 months from date of despatch.
Gene ID 102657
Other Names CD276 antigen, B7 homolog 3, B7-H3, Costimulatory molecule, CD276, Cd276, B7h3
Target/Specificity Rat anti Mouse CD276 antibody, clone MJ8 specifically recognizes mouse CD276, otherwise known as B7-H3, a ubiquitously expressed transmembrane glycoprotein and member of the B7 family of co-stimulatory molecules, which acts as both a positive and negative regulator of T-cell-mediated immune responses.CD276 is highly expressed in bone during embryogenesis, and can be induced on dendritic cells and monocytes by inflammatory cytokines. CD276 has been implicated in the development of acute and chronic transplant rejection, and is reported to have therapeutic potential as a regulator of cell-mediated immune responses to cancer, particularly in conjunction with anti-angiogenic therapy. In mice, CD276 has been linked with the development of pathogenic Th2 cells during the induction phase of allergic asthma (Nagashima et al. 2008).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Mouse CD276 Antibody, clone MJ8 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD12696
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