|Application ||FC, IP|
|Calculated MW||143269 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Shelf Life||18 months from date of despatch.|
|Other Names||Receptor-type tyrosine-protein phosphatase C, 22.214.171.124, Leukocyte common antigen, L-CA, T200, CD45, Ptprc|
|Target/Specificity||Mouse anti Rat CD45 antibody, clone OX-29 recognizes rat CD45, also known as Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen (LCA) or T200, expressed on all rat leukocytes. CD45 is a single pass, type I transmembrane glycoprotein of ~180-240kDa depending on the isoform and degree of glycosylation. Rat CD45 contains two intracellular tyrosine-protein phosphatase domains and at least two extracellular fibronectin type-III domains (Uniprot Acc no: P04157), although the existence of a third similar domain has previously been proposed (Symonset al.1999).Mouse anti Rat CD45 antibody, clone OX-29 has been reported as recognizing a monomorphic determinant present on all allogenic forms of the rat CD45 antigen (Symons and Barclay 2000). Epitope mapping further indicates that the OX-29 clone binds to a determinant located within the membrane distal two domains of CD45 (Symons,et al.1999).|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ for one month or at -20℃ for longer.|
|Precautions||Anti Rat CD45 Antibody, clone OX-29 is for research use only and not for use in diagnostic or therapeutic procedures.|
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