|Calculated MW||25644 Da|
|Purification||Purified IgG prepared by ion exchange chromatography|
|Immunogen||Recombinant human TNF-alpha.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Tumor necrosis factor, Cachectin, TNF-alpha, Tumor necrosis factor ligand superfamily member 2, TNF-a, Tumor necrosis factor, membrane form, N-terminal fragment, NTF, Intracellular domain 1, ICD1, Intracellular domain 2, ICD2, C-domain 1, C-domain 2, Tumor necrosis factor, soluble form, TNF, TNFA, TNFSF2|
|Target/Specificity||Mouse anti Human TNF alpha antibody, clone B-C7 recognizes human tumor necrosis factor, also known as Cachectin or Tumor necrosis factor ligand superfamily member 2. TNFα exists as a 233 amino acid membrane bound form, a single pass type II transmembrane protein which can be cleaved between residues 76 and 77 by ADAM17, also known as CD156b to yield the 157 amino acid soluble form of TNFα (UniProt: P01375).Mouse anti Human TNF alpha antibody, clone B-C7 recognizes both natural and bacterially producted recombinant human TNF-alpha and has an affinity of Kd = 0.5nM. Mouse anti Human TNF alpha antibody, clone B-C7 demonstrates neutralising activity against human TNF-alpha. Removal of sodium azide is recommended prior to functional assays - The use of EQU003 is recommended for this purpose.|
|Preservative & Stabilisers||0.09%Sodium Azide|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human TNF Alpha Antibody, clone B-C7 is for research use only and not for use in diagnostic or therapeutic procedures.|
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