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>   home   >   Products   >   Primary Antibodies   >   Anti Sheep MHC Class I Antibody, clone VPM19    

Anti Sheep MHC Class I Antibody, clone VPM19

Mouse Anti-Sheep Monoclonal Antibody

  • FC - Anti Sheep MHC Class I Antibody, clone VPM19  ABD12910
    Sheep peripheral blood lymphocytes stained with Mouse anti Sheep MHC Class I followed by Goat anti Mouse IgG:FITC
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Reactivity Sheep
Host Mouse
Clonality Monoclonal
Isotype IgG1
Clone Names VPM19
Additional Information
Other Species Cat
Purification Purified IgG prepared by affinity chromatography on Protein A from tissue culture supernatant
Immunogen Sheep T cells.
Shelf Life 18 months from date of despatch.
Target/Specificity Mouse anti Sheep MHC Class I monoclonal antibody, clone VPM19 recognizes the ovine homologue of the human MHC Class I, a monomorphic determinant expressed on the heavy chain of sheep MHC Class I, (OLA Class I).The major histocompatibility complex (MHC) is a cluster of genes that are important in the immune response to infections. In sheep, this is often referred to as the ovine leukocyte antigen (OLA) region. Ovine MHC Class I functions in the recognition and presentation of foreign antigens to T-cells.Ovine MHC Class I is a membrane glycoprotein with a molecular weight of approximately 44kDa, expressed on the cell surface of all peripheral blood leucocytes.Clone VPM19 has been in used in studies on a number of domestic animal diseases, in particular Maedi Visna virus infection, a disease of significant inportance in commercial sheep flocks (Leeet al.1996,Ryanet. al.2000andWuet. al.2008). Clone VPM19 has been cited as recognising MHC class I in some other species and has been used in a study of Feline herpes virus infection (Montagnaroet. al.2009).
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Sheep MHC Class I Antibody, clone VPM19 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD12910
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