|Application ||WB, IHC-P|
|Calculated MW||61149 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Polypeptide from the 50 kDa subunit of heparanase.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Heparanase, 188.8.131.52, Endo-glucoronidase, Heparanase-1, Hpa1, Heparanase 8 kDa subunit, Heparanase 50 kDa subunit, HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1|
|Target/Specificity||Mouse anti Human Heparanase-1 antibody, clone HP3/17 recognizes heparanase-1, also know as HPA1, an endo-beta-D-glucuronidase that degrades heparan sulfate proteoglycans (HSPGs) in the extracellular matrix through cleavage of the heparan sulfate side chains. Heparanase-1 is a heterodimer that is produced as a 65 kDa latent precursor, consisting of an 8 kDa subunit, a 50 kDa subunit and a linker peptide. Activation of Heparanase-1 occurs through cleavage of the linker peptide, releasing the 8 kDa subunit from the active 50 Da subunit.Mouse anti Heparanase-1 has been reported to recognize heparanase-1 in xenopus by western blotting (Bertolesiet al.2008)|
|Preservative & Stabilisers||0.01% Thiomersal|
|Storage||Store at -20℃ only.|
|Precautions||Anti Human Heparanase-1 Antibody, clone HP3/17 is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
email@example.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
If you have used an Abgent product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at firstname.lastname@example.org.
Request Quote Here