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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Anti Human Heparanase-1 Antibody, clone HP3/17    

Anti Human Heparanase-1 Antibody, clone HP3/17

Mouse Anti-Human Monoclonal Antibody

Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession Q9Y251
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2b
Clone Names HP3/17
Calculated MW 61149 Da
Additional Information
Other Species M,X
Purification Purified IgG prepared by affinity chromatography on Protein G
Immunogen Polypeptide from the 50 kDa subunit of heparanase.
Shelf Life 18 months from date of despatch.
Gene ID 10855
Other Names Heparanase,, Endo-glucoronidase, Heparanase-1, Hpa1, Heparanase 8 kDa subunit, Heparanase 50 kDa subunit, HPSE, HEP, HPA, HPA1, HPR1, HPSE1, HSE1
Target/Specificity Mouse anti Human Heparanase-1 antibody, clone HP3/17 recognizes heparanase-1, also know as HPA1, an endo-beta-D-glucuronidase that degrades heparan sulfate proteoglycans (HSPGs) in the extracellular matrix through cleavage of the heparan sulfate side chains. Heparanase-1 is a heterodimer that is produced as a 65 kDa latent precursor, consisting of an 8 kDa subunit, a 50 kDa subunit and a linker peptide. Activation of Heparanase-1 occurs through cleavage of the linker peptide, releasing the 8 kDa subunit from the active 50 Da subunit.Mouse anti Heparanase-1 has been reported to recognize heparanase-1 in xenopus by western blotting (Bertolesiet al.2008)
Preservative & Stabilisers 0.01% Thiomersal
Storage Store at -20℃ only. 
PrecautionsAnti Human Heparanase-1 Antibody, clone HP3/17 is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13075
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