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Anti Human PAI-1 Antibody

Goat Anti-Human Polyclonal Antibody

  • WB - Anti Human PAI-1 Antibody  ABD13264
    Western blot analysis of human liver lysate probed with Goat anti Human PAI-1 antibody
  • IHC-P - Anti Human PAI-1 Antibody  ABD13264
    Immunohistochemical staining of formalin fixed, paraffin embedded human placenta stained with Goat anti Human PAI-1 antibody following heat mediated antigen retrieval in citrate buffer (pH6.0)
  • IHC-P - Anti Human PAI-1 Antibody  ABD13264
    Immunohistochemical staining of formalin fixed, paraffin embedded human placenta stained with Goat anti Human PAI-1 antibody following heat mediated antigen retrieval in Tris/EDTA buffer (pH9.0)
  • E - Anti Human PAI-1 Antibody  ABD13264
    ELISA analysis of human PAI-1 expression using Goat anti Human PAI-1 antibody (1.5μml-1 as a detection reagent in a sandwich ELISA configuration
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05121
Reactivity Human
Host Goat
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 45060 Da
Additional Information
Immunogen Peptide with sequence C-GFKIDDKGMAPALRH, corresponding to the internal region of PAI-1 (NP_000593.1).
Shelf Life 18 months from date of despatch.
Gene ID 5054
Other Names Plasminogen activator inhibitor 1, PAI, PAI-1, Endothelial plasminogen activator inhibitor, Serpin E1, SERPINE1, PAI1, PLANH1
Target/Specificity Goat anti human PAI-1 antibody recognizes human Plasminogen activator inhibitor 1 (PAI-1), also known as Serpin E1. PAI-1 is a 402 amino acid }45kDa serine protease inhibitor epitope within the internal region of human Serpin E1. PAI-1 (Serpin E1) is a 45kD serine protease inhibitor and the principle inhibitor of tissue plasminogen activator (tPA) and urokinase (uPA)PAI-1 is present in plasma, platelets and endothelial cells, is expressed at increased levels in various disease states (Kruithofet al.1988), and has been linked to an increased occurrence of thrombosis in obesity and coronary artery disease (Oseroffet al.1989). Defects in PAI-1 are characterized by abnormal bleeding (Takahashiet al.1996).Goat anti human PAI-1 antibody has been used successfully for the detection of PAI-1 in human tissues by immunohistochemistry, western blotting and ELISA.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃ or at -20℃ if preferred.
PrecautionsAnti Human PAI-1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13264
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