|Calculated MW||55423 Da|
|Immunogen||Synthetic peptide: N-terminal region of human xCT.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Cystine/glutamate transporter, Amino acid transport system xc-, Calcium channel blocker resistance protein CCBR1, Solute carrier family 7 member 11, xCT, SLC7A11|
|Target/Specificity||Rabbit anti human xCT (N-terminal) antibody detects an epitope within the N-terminal (NT) of the cysteine/glutamate transporter xCT, which forms a complex with the 4F2 heavy chain (CD98), via a disulfide bond. This heterodimer forms a Na+ independent amino acid transport system which leads to the uptake of extracellular L-cystine in conjunction to L-glutamate efflux. This system is thought to play an important role in the protection of neurons and activated macrophages against oxidative stress.xCT is the receptor which mediates Kaposi's sarcoma herpesvirus (KSHV) cell fusion.|
|Preservative & Stabilisers||0.1%Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human xCT (N-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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