|Application ||WB, E|
|Calculated MW||49880 Da|
|Immunogen||Peptide sequence C-DGEVIKESKQEHKD from the C-terminal region of GFAP (NP_002046.1).|
|Shelf Life||18 months from date of despatch.|
|Other Names||Glial fibrillary acidic protein, GFAP, GFAP|
|Target/Specificity||ABD13313 recognises an epitope within the C-terminal (CT) region of human GFAP (glial fibrillary acidic protein), a class III intermediate filament (IF) protein specifically expressed by glial cells or cells of glial origin e.g astrocytes, ependymal cells and Schwann cells.GFAP plays a role in several cellular functions within the central nervous system (CNS), including cell structure and stability, communication, motility and mitosis, and is rapidly synthesized during astrogliosis, following trauma/injury. Mutations in the GFAP gene are responsible for the rare autosomal dominant disorder known as Alexander disease, resulting in the destruction of brain white matter and the formation of fibrous, eosinophilic deposits known as Rosenthal fibers. Characteristics of this disease are associated with transgenes and other mutation types in mouse.|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human GFAP (C-Terminal) Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
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