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Anti Human Wilms Tumour 1 Antibody

Rabbit Anti-Human Polyclonal Antibody

  • IHC-P - Anti Human Wilms Tumour 1 Antibody  ABD13354
    Staining of formalin fixed, paraffin embedded human kidney with Rabbit anti Human Wilms tumour 1
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P19544
Reactivity Human
Host Rabbit
Clonality Polyclonal
Isotype Polyclonal IgG
Calculated MW 49188 Da
Additional Information
Immunogen A synthetic peptide corresponding to amino acid sequence from the C-terminus of human WT1.
Shelf Life 18 months from date of despatch.
Gene ID 7490
Other Names Wilms tumor protein, WT33, WT1
Target/Specificity Rabbit anti Human Wilms Tumor 1 antibody recognises Wilms Tumor 1, also known asWT1 or WT33. WT1 is a 449 amino acid transcription factor that plays an important role in cellular development, in particular the development of the urogenital system, additionally WT1 functions in both the role of a tumor suppressor and in an oncogenic manner in tumor formation.Defects in the the WT1 gene result in a range of disease states including Frasier syndrome (FS) characterised by progressive nephropathy, male pseudohermaphroditism with no Wils tumor (Kohsakaet al.1999), Wilms Tumour 1 (WT1) an embryonal renal malignancy (Littleet al.1992) and Denys-Drash syndrome (DDS) and autosomal dominant nephropathy with genital abnormalities with or without Wils tumor (Bairdet al.1992)WT1 is expressed in the Kidney and a subset of haematopietic cells. Multiple isoforms of WT1 have so far been recognised. Rabbit anti Human Wilms Tumor 1 antibody is expected to recognize the canonical isoform 1 and other isoforms with a normally presented C-terminal region.
Preservative & Stabilisers 0.09% Sodium Azide (NaN3)
Storage Store at +4℃.DO NOT FREEZE.
PrecautionsAnti Human Wilms Tumour 1 Antibody is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD13354
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