|Application ||WB, IHC-P, IF, E, IP|
|Calculated MW||96023 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein G|
|Immunogen||Alix fusion protein.|
|Shelf Life||18 months from date of despatch.|
|Other Names||Programmed cell death 6-interacting protein, PDCD6-interacting protein, ALG-2-interacting protein 1, ALG-2-interacting protein X, Hp95, PDCD6IP, AIP1, ALIX, KIAA1375|
|Target/Specificity||Mouse anti ALIX antibody, clone 3A9 recognizes the apoptosis-linked gene-2 interacting protein X (ALIX), also known as Programmed cell death 6-interacting protein or Hp95. ALIX is a 868 amino acid ~90kDa cytoplasmic protein containing a single BRO1 domain implicated in endosomal targeting (Kimet al.2005).ALIX was first reported to play a role in apoptosis dependent on its association with PDCD6(Mahul-Mellieret al.2006) but has subsequently shown to be involved in endocytosis (Matsuoet al.2004), viral budding (Irieet al.2008) and actin cytoskeletal assembly (Panet al.2006).Mouse anti Alix, clone 3A9 has been used extensively for the detection of ALIX by Western blotting and for the identification of an ALIX homologue in the sea urchin Paracentrotus lividus(Romancinoet al.2013).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti ALIX Antibody, clone 3A9 is for research use only and not for use in diagnostic or therapeutic procedures.|
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