|Application ||WB, IHC-F, IF, FC, E|
|Other Accession||P02745, P02746|
|Calculated MW||25774 Da|
|Purification||Purified IgG prepared by affinity chromatography on Protein A|
|Immunogen||Globular head domain of C1q, purified from human plasma.|
|Shelf Life||18 months from the date of despatch.|
|Other Names||Complement C1q subcomponent subunit C, C1QC, C1QG|
|Target/Specificity||Mouse anti human C1q antibody, clone 3R9/2, recognizes human complement component 1 q (C1q), a 156kDa secreted protein. C1q associates with proenzymes C1r and C1s to form the calcium-dependent C1 complex, the first component of the serum complement system. C1q is composed of six A-, six B-chains and six C-polypeptide chains. Each chain contains a collagen-like region located near the N-terminus and a C-terminal globular region. These regions bind the Fc region of IgM and IgG molecules, initiating the classical pathway of complement activation. C1q deficiency has been associated with lupus erythematosus and glomerulonephritis (Troedsonet al.2013).|
|Preservative & Stabilisers||0.09% Sodium Azide (NaN3)|
|Storage||Store at +4℃ or at -20℃ if preferred.|
|Precautions||Anti Human C1q Antibody, clone 3R9/2 is for research use only and not for use in diagnostic or therapeutic procedures.|
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