|Calculated MW||26416 Da|
|Shelf Life||3 months from date of reconstitution.|
|Other Names||Fms-related tyrosine kinase 3 ligand, Flt3 ligand, Flt3L, SL cytokine, FLT3LG|
|Target/Specificity||Recombinant Human Flt3 Ligandis an E. coliderived polypeptide corresponding to the human Flt3 ligand, a soluble polypeptide comprising the extracellular domain of the transmembrane flt-3 ligand protein.Flt-3 ligand stimulates the proliferation and colony formation of certain BM precursor cells, including CD34 +ve cells. The biological activity was determined by dose-dependent stimulation of the proliferation of human AML5 cells giving an ED50 of 1.0ng/ml.|
|Storage||Prior to reconstitution store at +4oC. Following reconstitution store at -20oC.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this pro|
|Precautions||Recombinant Human Flt3 Ligand is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Timeus, F. et al. (1998) Cell adhesion molecule expression in cord blood CD34+ cells. Stem Cells. 16: 120 - 126. 2. Casazza, A. et al. (2011) Systemic and targeted delivery of semaphorin 3A inhibits tumor angiogenesis and progression in mouse tumor models.Arterioscler Thromb Vasc Biol. 31: 741-9.
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