|Calculated MW||43779 Da|
|Shelf Life||18 months from date of despatch.|
|Other Names||Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP, Testosterone-estradiol-binding globulin, TeBG, Testosterone-estrogen-binding globulin, SHBG|
|Target/Specificity||Purified Human sex hormone binding globulin, is a ~90 kDa homodimeric glycoprotein composed of two 45 kDa subunits linked via disulphide bridges. It is an androgen transport protein which binds and regulates the free concentration of steroid hormones and is involved in steroid signalling at the cell membrane.|
|Storage||Store at -20oC only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation|
|Precautions||Purified Human Sex Hormone Binding Globulin is for research use only and not for use in diagnostic or therapeutic procedures.|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abgent to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
1. Rosner, W. et al. (1999) Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane. J. Steroid Biochem. Mol. Biol. 69: 481-485. 2. Kahn, S. et al. (2002) Sex hormone-binding globulin is synthesized in target cells. J. Endocrinol. 175: 113–120. 3. Zheng X et al. (2015) Analysis of Hormone-Protein Binding in Solution by Ultrafast Affinity Extraction: Interactions of Testosterone with Human Serum Albumin and Sex Hormone Binding Globulin.Anal Chem. Oct 20. [Epub ahead of print]
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