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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   Purified Human Sex Hormone Binding Globulin    

Purified Human Sex Hormone Binding Globulin

     
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Product Information
Primary Accession P04278
Reactivity Human
Calculated MW 43779 Da
Additional Information
Shelf Life 18 months from date of despatch.
Gene ID 6462
Other Names Sex hormone-binding globulin, SHBG, Sex steroid-binding protein, SBP, Testis-specific androgen-binding protein, ABP, Testosterone-estradiol-binding globulin, TeBG, Testosterone-estrogen-binding globulin, SHBG
Target/Specificity Purified Human sex hormone binding globulin, is a ~90 kDa homodimeric glycoprotein composed of two 45 kDa subunits linked via disulphide bridges. It is an androgen transport protein which binds and regulates the free concentration of steroid hormones and is involved in steroid signalling at the cell membrane.
Storage Store at -20oC only.Storage in frost-free freezers is not recommended.This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation
PrecautionsPurified Human Sex Hormone Binding Globulin is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations (0)

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References

1. Rosner, W. et al. (1999) Sex hormone-binding globulin mediates steroid hormone signal transduction at the plasma membrane.
J. Steroid Biochem. Mol. Biol. 69: 481-485. 2. Kahn, S. et al. (2002) Sex hormone-binding globulin is synthesized in target cells.
J. Endocrinol. 175: 113–120. 3. Zheng X et al. (2015) Analysis of Hormone-Protein Binding in Solution by Ultrafast Affinity Extraction: Interactions of Testosterone with Human Serum Albumin and Sex Hormone Binding Globulin.
Anal Chem. Oct 20. [Epub ahead of print]

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Cat# ABD14364
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