|Calculated MW||50662 Da|
|Shelf Life||3 months from date of reconstitution.|
|Other Names||Growth/differentiation factor 6, GDF-6, Bone morphogenetic protein 13, BMP-13, Growth/differentiation factor 16, GDF6, BMP13, GDF16|
|Target/Specificity||Bone morphogenetic protein 13 (BMP-13), otherwise known as growth differentiation factor 6 (GDF6), is expressed in hypertrophic chondrocytes during embryonic development of long bones, and implicated as a regulator of the growth and maintenance of articular cartilage. BMP-13 is also expressed at the boundaries of developing carpals, tarsals, and vertebrae, and mutations in the BMP-13 gene, have been identified in both familial and sporadic cases of Klippel-Feil syndrome (KFS), a congenital disorder of spinal segmentation. Functional BMP-13 is a disulfide-linked homodimer consisting of two 120 amino acid polypeptide chains, derived by proteolytic processing of a biologically inactive precursor protein.|
|Storage||Prior to reconstitution store at +4oC.After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this produc|
|Precautions||Recombinant Human BMP-13 is for research use only and not for use in diagnostic or therapeutic procedures.|
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