|Calculated MW||35386 Da|
|Shelf Life||3 months from date of reconstitution.|
|Other Names||Secreted frizzled-related protein 1, FRP-1, sFRP-1, Secreted apoptosis-related protein 2, SARP-2, SFRP1, FRP, FRP1, SARP2|
|Target/Specificity||Recombinant Human SFRP1 antigen produced in Hela cells corresponds to human SFRP1 (Secreted Frizzled-Related Protein-1), a widely expressed multi-functional secreted protein, and member of the sFRP family. SFRP1acts as a modulator of Wnt signalling, playing an important role in embryonic development as well as proliferation, differentiation, and apoptosis in adult tissues. SFRP1 acts as a promoter of Wnt-induced effects at lower concentrations, and as a negative regulator at high concentrations.SFRP1 has been implicated as a tumour suppressor protein in several human malignancies, including colorectal, breast, bladder, and ovarian cancer.Recombinant Human SFRP1 is a 283 amino acid residue glycosylated protein containing a cystene-rich Frizzled homologous domain.|
|Storage||Prior to reconstitution store at +4oC.After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this produc|
|Precautions||Recombinant Human SFRP1 is for research use only and not for use in diagnostic or therapeutic procedures.|
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