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Recombinant Human SFRP1

Product Information
Primary Accession Q8N474
Reactivity Human
Calculated MW 35386 Da
Additional Information
Shelf Life 3 months from date of reconstitution.
Gene ID 6422
Other Names Secreted frizzled-related protein 1, FRP-1, sFRP-1, Secreted apoptosis-related protein 2, SARP-2, SFRP1, FRP, FRP1, SARP2
Target/Specificity Recombinant Human SFRP1 antigen produced in Hela cells corresponds to human SFRP1 (Secreted Frizzled-Related Protein-1), a widely expressed multi-functional secreted protein, and member of the sFRP family. SFRP1acts as a modulator of Wnt signalling, playing an important role in embryonic development as well as proliferation, differentiation, and apoptosis in adult tissues. SFRP1 acts as a promoter of Wnt-induced effects at lower concentrations, and as a negative regulator at high concentrations.SFRP1 has been implicated as a tumour suppressor protein in several human malignancies, including colorectal, breast, bladder, and ovarian cancer.Recombinant Human SFRP1 is a 283 amino acid residue glycosylated protein containing a cystene-rich Frizzled homologous domain.
Storage Prior to reconstitution store at +4oC.After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this produc
PrecautionsRecombinant Human SFRP1 is for research use only and not for use in diagnostic or therapeutic procedures.
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Cat# ABD14421
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