|Other Accession||P01873, P01872|
|Calculated MW||11934 Da|
|Shelf Life||18 months from date of despatch.|
|Other Names||Ig kappa chain C region, IGKC|
|Target/Specificity||Intended UseTarget SpeciesMouseProduct FormPurified monoclonal IgM - liquidReconstitutionPreparationPurified IgM prepared by affinity chromatography from tissue culture supernatantPreservative Stabilisers0.1%Sodium AzidePuritySingle band by agarose electrophoresis and immunoelectrophoresis.Approx. Protein ConcentrationsIgM concentration 1.0 mg/mlReagents In The KitPreparing The AntibodyTest PrincipleBuffer SolutionPhosphate buffered salineStorageStore at +4oC or at -20oC if preferred.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend microcentrifugation before use.Shelf Life18 months from date of despatch.GO TermsGO:0000187activation of MAPK activityRelated reagentsGO:0042571immunoglobulin complex, circulatingRelated reagentsGO:0043410positive regulation of MAPKKK cascadeRelated reagentsGO:0003823antigen bindingRelated reagentsGO:0050853B cell receptor signaling pathwayRelated reagentsGO:0019882antigen processing and presentationRelated reagentsGO:0045807positive regulation of endocytosisRelated reagentsGO:0050731positive regulation of peptidyl-tyrosine phosphorylationRelated reagentsGO:0004888transmembrane receptor activityRelated reagentsGO:0016021integral to membraneRelated reagentsGO:0009897external side of plasma membraneRelated reagentsGO:0045022early endosome to late endosome transportRelated reagentsGO:0048471perinuclear region of cytoplasmRelated reagentsGO:0002455humoral immune response mediated by circulating immunoglobulinRelated reagentsGO:0030890positive regulation of B cell proliferationRelated reagentsGO:0019815B cell receptor complexRelated reagentsGO:0005515protein bindingRelated reagentsUniProtP01837Related reagentsP01873Related reagentsP01872Related reagentsEntrez GeneIghmRelated reagentsIgk-CRelated reagentsAcknowledgementsRegulatoryFor research purposes only|
|Storage||Store at +4oC or at -20oC if preferred.This product should be stored undiluted.Storage in frost-free freezers is not recommended. Avoid repeated freezing and thawing as this may denature the protein. Should this product contain a precipitate we recommend|
|Precautions||Mouse IgM Kappa, clone MADNP-5 is for research use only and not for use in diagnostic or therapeutic procedures.|
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Provided below are standard protocols that you may find useful for product applications.
1. Hayer, S. et al. (2008) B-cell infiltrates induce endosteal bone formation in inflammatory arthritis.J Bone Miner Res. 23: 1650-60. 2. Rohrer, J.W. et al. (2006) Identification of oncofetal antigen/immature laminin receptor protein epitopes that activate BALB/c mouse OFA/iLRP-specific effector and regulatory T cell clones.J Immunol. 176: 2844-56.
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