|Calculated MW||60649 Da|
|Shelf Life||3 months from date of reconstitution.|
|Other Names||Macrophage colony-stimulating factor 1, CSF-1, MCSF, Processed macrophage colony-stimulating factor 1, Csf1, Csfm|
|Target/Specificity||M-CSF (Macrophage colony-stimulating factor) is a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells. Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor). A genetic defect in M-CSF is responsible for osteopetrosis in mice (op/op), which are severely deficient in mature macrophages and have a restricted capacity for bone remodelling.|
|Storage||Prior to reconstitution store at +4oC.After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this produc|
|Precautions||Recombinant Mouse M-CSF is for research use only and not for use in diagnostic or therapeutic procedures.|
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