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Recombinant Mouse M-CSF

     
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Product Information
Primary Accession P07141
Reactivity Mouse
Calculated MW 60649 Da
Additional Information
Shelf Life 3 months from date of reconstitution.
Gene ID 12977
Other Names Macrophage colony-stimulating factor 1, CSF-1, MCSF, Processed macrophage colony-stimulating factor 1, Csf1, Csfm
Target/Specificity M-CSF (Macrophage colony-stimulating factor) is a potent lineage restricted haematopoietic growth factor and member of the CSF family of hormone-like glycoproteins, which plays a key role in the regulation of cellular differentiation, proliferation, and the survival of blood monocytes, tissue macrophages and their progenitor cells. Along with sRANKL/CD254/OPGL, M-CSF is essential for osteoclastogenesis, acting through the tyrosine kinase receptor c-fms (colony stimulating factor 1 receptor). A genetic defect in M-CSF is responsible for osteopetrosis in mice (op/op), which are severely deficient in mature macrophages and have a restricted capacity for bone remodelling.
Storage Prior to reconstitution store at +4oC.After reconstitution store at -20oC.Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the antibody. Should this produc
PrecautionsRecombinant Mouse M-CSF is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
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Cat# ABD14498
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