|Application ||WB, IHC-P, E|
|Description||Rabbit IgG polyclonal antibody for Uteroglobin detection. Tested with WB, IHC-P, Direct ELISA in Mouse;Rat.|
|Reconstitution||Add 0.2ml of distilled water will yield a concentration of 500ug/ml.|
|Other Names||Uteroglobin, Clara cell phospholipid-binding protein, CCPBP, Clara cells 10 kDa secretory protein, CC10, PCB-binding protein, Secretoglobin family 1A member 1, Scgb1a1, Cc10, Ugb, Utg|
|Calculated MW||10449 Da|
|Application Details||Western blot, 0.1-0.5 µg/ml|
Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml
Direct ELISA, 0.1-0.5 µg/ml
|Tissue Specificity||Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).|
|Contents||Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.|
|Immunogen||E. coli-derived rat Uteroglobin recombinant protein (Position: S20-V96).|
|Cross Reactivity||No cross reactivity with other proteins.|
|Storage||At -20˚C; for one year. After r˚Constitution, at 4˚C; for one month. It˚Can also be aliquotted and stored frozen at -20˚C; for a longer time. Avoid repeated freezing and thawing.|
|Synonyms||Cc10, Ugb, Utg|
|Function||Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.|
|Tissue Location||Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways)|
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Provided below are standard protocols that you may find useful for product applications.
Uteroglobin, also known as secretoglobin family 1A member 1 (SCGB1A1), is a protein that in humans is encoded by the SCGB1A1 gene. This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation, inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
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