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Anti-Lumican Picoband Antibody

     
  • WB - Anti-Lumican Picoband Antibody ABO12348
    Anti- Lumican Picoband antibody, ABO12348, Western blottingAll lanes: Anti Lumican (ABO12348) at 0.5ug/mlLane 1: Mouse Testis Tissue Lysate at 50ugLane 2: Mouse Thymus Tissue Lysate at 50ugLane 3: NIH3T3 Whole Cell Lysate at 40ugPredicted bind size: 38KDObserved bind size: 60KD
  • IHC - Anti-Lumican Picoband Antibody ABO12348
    Anti- Lumican Picoband antibody, ABO12348, IHC(P)IHC(P): Mouse Brain Tissue
  • SPECIFICATION
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P51885
Host Rabbit
Reactivity Mouse
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Lumican(LUM) detection. Tested with WB, IHC-P, ELISA in Mouse.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 17022
Other Names Lumican, Keratan sulfate proteoglycan lumican, KSPG lumican, Lum, Lcn, Ldc
Calculated MW 38265 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Mouse, By Heat

ELISA , 0.1-0.5 µg/ml, Mouse, -
Western blot, 0.1-0.5 µg/ml, Mouse
Subcellular Localization Secreted, extracellular space, extracellular matrix .
Tissue Specificity Cornea and other tissues.
Protein Name Lumican
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E. coli-derived mouse Lumican recombinant protein (Position: I68-N338). Mouse Lumican shares 88.9% and 98.2% amino acid (aa) sequence identity with human and rat Lumican, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name Lum
Synonyms Lcn, Ldc
Cellular Location Secreted, extracellular space, extracellular matrix
Tissue Location Cornea and other tissues.
Research Areas
Citations (0)

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Background

Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.

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$ 280.00
Cat# ABO12348
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