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>   home   >   Products   >   Primary Antibodies   >   Cancer   >   Anti-n-Myc Picoband Antibody   

Anti-n-Myc Picoband Antibody

     
  • WB - Anti-n-Myc Picoband Antibody ABO12414
    Anti- n-Myc Picoband antibody, ABO12414, Western blottingAll lanes: Anti n-Myc (ABO12414) at 0.5ug/mlLane 1: Rat Brain Tissue Lysate at 50ugLane 2: A431 Whole Cell Lysate at 40ugLane 3: MCF-7 Whole Cell Lysate at 40ugLane 4: SW620 Whole Cell Lysate at 40ugPredicted bind size: 50KDObserved bind size: 50KD
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB
Primary Accession P04198
Host Rabbit
Reactivity Human, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for N-myc proto-oncogene protein(MYCN) detection. Tested with WB in Human;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 4613
Other Names N-myc proto-oncogene protein, Class E basic helix-loop-helix protein 37, bHLHe37, MYCN, BHLHE37, NMYC
Calculated MW 49561 MW KDa
Application Details Western blot, 0.1-0.5 µg/ml, Human, Rat
Subcellular Localization Nucleus.
Tissue Specificity Expressed in the neuronal cells of the cerebrum, neuroblastomas and thyroid tumors (at protein level). .
Protein Name N-myc proto-oncogene protein
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen A synthetic peptide corresponding to a sequence at the C-terminus of human n-Myc (428-464aa EYVHSLQAEEHQLLLEKEKLQARQQQLLKKIEHARTC), different from the related mouse and rat sequences by two amino acids.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins.
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name MYCN
Synonyms BHLHE37, NMYC
Function Positively regulates the transcription of MYCNOS in neuroblastoma cells.
Cellular Location Nucleus.
Tissue Location Expressed in the neuronal cells of the cerebrum, neuroblastomas and thyroid tumors (at protein level)
Research Areas
Citations (0)

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Background

N-myc proto-oncogene protein, also known as N-Myc or basic helix-loop-helix protein 37 (bHLHe37), is a protein that in humans is encoded by the MYCN gene. This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. And this protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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$ 240.00
Cat# ABO12414
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