|Description||Rabbit IgG polyclonal antibody for Cathepsin G(CTSG) detection. Tested with WB in Mouse.|
|Reconstitution||Add 0.2ml of distilled water will yield a concentration of 500ug/ml.|
|Other Names||Cathepsin G, 184.108.40.206, Vimentin-specific protease, VSP, Ctsg|
|Calculated MW||29096 MW KDa|
|Application Details||Western blot, 0.1-0.5 µg/ml, Mouse|
|Subcellular Localization||Membrane. Strongly associated with membranes.|
|Protein Name||Cathepsin G|
|Contents||Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.|
|Immunogen||E.coli-derived mouse Cathepsin G recombinant protein (Position: I21-T261). Mouse Cathepsin G shares 70.2% amino acid (aa) sequence identity with human Cathepsin G.|
|Purification||Immunogen affinity purified.|
|Cross Reactivity||No cross reactivity with other proteins.|
|Storage||At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.|
|Function||This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis.|
|Cellular Location||Membrane. Note=Strongly associated with membranes|
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Provided below are standard protocols that you may find useful for product applications.
Cathepsin G is an enzymatic protein belonging to the peptidase or protease families. In humans, it is coded by the CTSGÂ gene.Â This gene is mapped to 14q12. In transgenic mice, it was found thatÂ human Cathepsin G gene was expressed in early myeloid precursors in a manner coordinate with the expression of the endogenous murine gene in the bone marrow and spleen. The protein encoded by thisÂ gene, a member of theÂ peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclearÂ leukocytes.Â The encoded protease has a specificity similar to that ofÂ chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and inÂ connective tissueÂ remodeling at sites ofÂ inflammation.Â
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