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Anti-CXCL5/ENA-78 Antibody

     
  • WB - Anti-CXCL5/ENA-78 Antibody ABO12545
    Western blot analysis of CXCL5 expression in recombinant rat CXCL5 protein 0.5ng (lane 1). CXCL5 at 14KD was detected using rabbit anti- CXCL5 Antigen Affinity purified polyclonal antibody (Catalog # ABO12545) at0.5 ??g/mL. The blot was developed using chemiluminescence (ECL) method .
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, E
Primary Accession P97885
Host Rabbit
Reactivity Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for C-X-C motif chemokine 5(CXCL5) detection. Tested with WB, ELISA in Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 60665
Other Names C-X-C motif chemokine 5, Cytokine LIX, Small-inducible cytokine B5, Cxcl5, Scyb5
Calculated MW 14263 MW KDa
Application Details ELISA , 0.1-0.5 µg/ml, Rat, -
Western blot, 0.1-0.5 µg/ml, Rat
Subcellular Localization Secreted.
Protein Name C-X-C motif chemokine 5
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E. coli-derived rat CXCL5 recombinant protein (Position: A38-Q130). Rat CXCL5 shares 58.7% and 76.3% amino acid (aa) sequence identity with human and mouse CXCL5, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins.
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name Cxcl5
Synonyms Scyb5
Function May participate in the recruitment of inflammatory cells by injured or infected tissue.
Cellular Location Secreted.
Research Areas
Citations (0)

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Background

C-X-C motif chemokine 5 or ENA-78 is a protein that in humans is encoded by the CXCL5 gene. The protein encoded by this gene, CXCL5 is a small cytokine belonging to the CXC chemokine family. It is produced following stimulation of cells with the inflammatory cytokines interleukin-1 or tumor necrosis factor-alpha. Expression of CXCL5 has also been observed ineosinophils, and can be inhibited with the type II interferon IFN-γ. This chemokine stimulates the chemotaxis of neutrophils possessing angiogenic properties. It elicits these effects by interacting with the cell surface chemokine receptor CXCR2. The gene for CXCL5 is encoded on four exons and is located on human chromosome 4 amongst several other CXC chemokine genes. CXCL5 has been implicated in connective tissue remodelling. Also, CXCL5 has been described to regulate neutrophil homeostasis.

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$ 240.00
Cat# ABO12545
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