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Anti-AGP1/alpha 1 acid glycoprotein Picoband Antibody

     
  • WB - Anti-AGP1/alpha 1 acid glycoprotein Picoband Antibody ABO12641
    Western blot analysis of ORM1 expression in rat liver extract (lane 1), mouse liver extract (lane 2) and PANC whole cell lysates (lane 3). ORM1 at 45KD was detected using rabbit anti-ORM1 Antigen Affinity purified polyclonal antibody (Catalog # ABO12641) at 0.5 μg/mL. The blot was developed using chemiluminescence (ECL) method .
  • IHC - Anti-AGP1/alpha 1 acid glycoprotein Picoband Antibody ABO12641
    ORM1 was detected in paraffin-embedded sections of human intestinal cancer tissues using rabbit anti- ORM1 Antigen Affinity purified polyclonal antibody (Catalog # ABO12641) at 1 ??g/mL. The immunohistochemical section was developed using SABC method .
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Product Information
Application
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • E=ELISA
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
WB, IHC-P, E
Primary Accession P02763
Host Rabbit
Reactivity Human, Mouse, Rat
Clonality Polyclonal
Format Lyophilized
Description Rabbit IgG polyclonal antibody for Alpha-1-acid glycoprotein 1(ORM1) detection. Tested with WB, IHC-P, ELISA in Human;Mouse;Rat.
Reconstitution Add 0.2ml of distilled water will yield a concentration of 500ug/ml.
Additional Information
Gene ID 5004
Other Names Alpha-1-acid glycoprotein 1, AGP 1, Orosomucoid-1, OMD 1, ORM1, AGP1
Calculated MW 23512 MW KDa
Application Details Immunohistochemistry(Paraffin-embedded Section), 0.5-1 µg/ml, Human, By Heat

ELISA , 0.1-0.5 µg/ml, Human, -
Western blot, 0.1-0.5 µg/ml, Human, Mouse, Rat
Subcellular Localization Secreted.
Tissue Specificity Expressed by the liver and secreted in plasma.
Protein Name Alpha-1-acid glycoprotein 1
Contents Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Immunogen E. coli-derived human ORM1 recombinant protein (Position: Q19-S201). Human ORM1 shares 47.5% and 48.1% amino acid (aa) sequence identity with mouse and rat ORM1, respectively.
Purification Immunogen affinity purified.
Cross Reactivity No cross reactivity with other proteins
Storage At -20˚C for one year. After r˚Constitution, at 4˚C for one month. It˚Can also be aliquotted and stored frozen at -20˚C for a longer time.Avoid repeated freezing and thawing.
Protein Information
Name ORM1
Synonyms AGP1
Function Functions as transport protein in the blood stream. Binds various ligands in the interior of its beta-barrel domain. Also binds synthetic drugs and influences their distribution and availability in the body. Appears to function in modulating the activity of the immune system during the acute-phase reaction.
Cellular Location Secreted.
Tissue Location Expressed by the liver and secreted in plasma.
Research Areas
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Background

Alpha-1-acid glycoprotein 1 is a protein that in humans is encoded by the ORM1 gene. The structural gene for orosomucoid (ORM1) is assigned to the end of the long arm of chromosome 9 by demonstration of linkage to ABO and AK1. This gene encodes a key acute phase plasma protein. Because of its increase due to acute inflammation, this protein is classified as an acute-phase reactant. The specific function of this protein has not yet been determined; however, it may be involved in aspects of immunosuppression.

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$ 280.00
Cat# ABO12641
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