|Calculated MW||17907 Da|
|Application & Usage||Western blot analysis (0.5-4 µg/ml). Recombinant human IFN-gamma can be used as a positive control. However, the optimal conditions should be determined individually.|
|Other Names||Interferon gamma, IFNg, IFN-gamma, IFN gamma|
|Formulation||100 µg (0.5 mg/ml) antigen affinity purified rabbit anti-murine IFN-gamma polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 50% glycerol, and 0.02% thimerosal.|
|Handling||The antibody solution should be gently mixed before use.|
|Reconstitution & Storage||-20 °C|
|Precautions||IFN gamma Antibody is for research use only and not for use in diagnostic or therapeutic procedures.|
|Function||Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons.|
|Tissue Location||Released primarily from activated T lymphocytes|
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Provided below are standard protocols that you may find useful for product applications.
IFN-gamma is a lymphoid factor that possesses potent anti-viral activity. It has also been shown that INF-gamma stimulates microphages and NK cells. Human IFN-gamma is a 16.9 kDa protein containing 144 amino acid residues.
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